Drew Barrymore, Salma Hayek, & More Stars Who Wowed at the 2025 Breakthrough Prize Ceremony

Once again, the annual Breakthrough Prize Ceremony has happened, and so many stars came dressed to impress for one of science’s biggest nights.

Unofficially known as the “Oscars for scientists,” so many stars arrived at the Barker Hanger on April 05 to honor “scientists changing the world.” The night honors three scientists for the awards of Breakthrough Prize in Mathematics, Breakthrough Prize in Fundamental Physics, and Breakthrough Prize in Life Sciences.

So, along with scientists receiving their flowers, we also see some of our favorite stars turn heads with their looks on the red carpet.

The big night always brings a lot of A-listers, some like Glenn Close, Olivia Wilde, and Jessica Chastain, coming for multiple years in a row. Then, we also get stars who make rare red carpet-appearances like Danny DeVito, Jodie Foster, and Gwyneth Paltrow. But no matter how frequently they come, so many stars come to turn heads!

From bold sparkling looks worn by stars like Kate Hudson and Lily Collins to truly dark ensembles like Gillian Anderson and Paris Hilton’s, this red carpet event was a must-see.

Below, see which celebrities wowed on the 11th Breakthrough Prize Ceremony red carpet.

Drew Barrymore at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Drew Barrymore

Drew Barrymore stunned in this black Carolina Herrera gown, which she paired with an Alexis Bittar bag, and Swarovski jewelry.

Jessica Chastain at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Jessica Chastain

Jessica Chastain looked sensational in this cutout, backless white Gucci gown, which she paired with Damiani jewelry and a silver clutch.

Gwyneth Paltrow at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Gwyneth Paltrow

Gwyneth Paltrow looked radiant in this white Donna Karan New York RE15 gown, which she paired with Messika earrings and Santoni shoes.

Paris Hilton at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Paris Hilton

Paris Hilton stunned in this elaborate, sparkling black gown.

Christina Aguilera at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Christina Aguilera

Christina Aguilera made jaws drop in this corsetted white gown from Dolce & Gabbana.

Glenn Close at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Glenn Close

Glenn Close looked so gorgeous as she donned a sparkling navy Giorgio Armani set, which she paired with matching Roger Vivier shoes and silver Neil Lane jewelry.

Gillian Anderson at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Gillian Anderson

Gillian Anderson turned heads in this black cubist-inspired Akris dress.

Danny DeVito at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Danny DeVito

Danny DeVito rocked this simple and chic black suit!

Maria Sharapova at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Maria Sharapova

Maria Sharapova wowed in this chic white Stephane Rolland gown (that has pockets)!

Jodie Foster at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Jodie Foster

Jodie Foster looked so sleek and chic in this all-white ensemble.

Marianne Fonseca at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Marianne Fonseca

Model and CEO of Gente Beauty Marianne Fonseca turned heads in this Tony Ward SS25 Couture gown which featured a draped black skirt and a swirled blue bodice.

Kate Hudson at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Kate Hudson

Kate Hudson looked like a glittering goddess in this shining Elie Saab Couture gown, which she paired with delicate Effy jewelry.

Salma Hayek Pinault at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Salma Hayek

Salma Hayek wowed in this black gown, which featured a sheer top and bold gold jewelry throughout.

Alicia Keys at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Alicia Keys

Alicia Keys was the definition of cool in this pinstripe Fear of God suit. 

Olivia Wilde at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Olivia Wilde

Olivia Wilde brought the gothic vibes in this off-the-shoulder black Erdem FW25 RTW gown, which she paired with Jennifer Meyer jewelry.

Lauren Sánchez, Jeff Bezos at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Lauren Sánchez & Jeff Bezos

Soon-to-be-married lovebirds Lauren Sánchez and Jeff Bezos arrived in sleek looks, with Sánchez in a silk red slip dress and Bezos in a simple tuxedo.

Ke Huy Quan at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Ke Huy Quan

Oscar-winning actor Ke Huy Quan looked so cool in this dark tux! 

Lily Collins at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Lily Collins

Lily Collins wowed in this sparkling black gown from Armani Privé.

Zoe Saldana at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Zoe Saldana

Oscar-winning actress Zoe Saldana wowed in this dark taupe Schiaparelli FW25 RTW gown.

Katy Perry at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Katy Perry

Katy Perry arrived in a swirled silver gown from Gaurav Gupta SS24 Couture.

Priscilla Chan, Mark Zuckerberg at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Priscilla Chan & Mark Zuckerberg

Priscilla Chan and Mark Zuckerberg coordinated in dark looks.

Lizzo at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Lizzo

Lizzo arrived in a draped, layered red Robert Wun couture gown.

Gal Gadot at The 11th Breakthrough Prize Ceremony held at Barker Hanger on April 05, 2025 in Santa Monica, California.

Gal Gadot

Gal Gadot arrived in a black fringed gown from Prada.

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